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. 2021 Dec 28;12(1):41. doi: 10.3390/biom12010041

Figure 2.

Figure 2

Estradiol (E2) prevents bone loss in ovariectomized (OVX) mice in vivo. (A) Representative 3D Micro-CT reconstructions of mouse femur from sham (PBS injection), OVX (PBS injection), and E2 (OVX with 0.1 mg/kg estradiol). (B) Quantitative bone morphometric parameters of bone mineral density (BMD, g/cm2), bone volume to total tissue volume (BV/TV), bone surface to tissue volume (BS/TV, mm−1), and trabecular number (Tb.N., mm−1) were measured. Values presented as the mean ± standard deviation (n = 3); * p < 0.05, ** p < 0.01, *** p < 0.001.