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. 2022 Jan 12;11(2):249. doi: 10.3390/cells11020249

Figure 2.

Figure 2

Example of true-positive and true-negative fluorescence signals in patients with colorectal carcinoma using SGM101, an anti-CEA antibody-based tumor-targeting probe. (A) Intraoperative fluorescence of a palpable colorectal tumor during surgery, with a TBR of 2.0 (true positive). (B) Absence of fluorescence in a tumor, which was confirmed as a pathological complete response by histopathology (true negative). TBR tumor-to-background ratio, NIR near-infrared. Adapted from de Valk et al. [77].