TABLE 2.
Identification of differentially expressed ferroptosis related genes.
| Gene | Normal mean | Tumor mean | Log2|FC| | p value | FDR |
|---|---|---|---|---|---|
| PTGS2 | 42.3182151 | 7.45442924 | −2.50510898 | 1.15E-10 | 6.49E-10 |
| DUSP1 | 261.631399 | 170.622883 | −0.61672455 | 1.86E-05 | 4.77E-05 |
| ALB | 2.09037758 | 4.1752973 | 0.99811537 | 6.53E-09 | 2.89E-08 |
| GPX2 | 13.4870552 | 3.92472467 | −1.78091203 | 5.19E-20 | 2.70E-18 |
| DDIT4 | 48.8324918 | 21.2101584 | −1.203086 | 5.00E-12 | 3.59E-11 |
| ASNS | 5.37772335 | 7.77466376 | 0.53178474 | 5.08E-17 | 9.62E-16 |
| TSC22D3 | 72.1468062 | 39.4798291 | −0.86981979 | 1.16E-06 | 3.56E-06 |
| TXNIP | 164.004415 | 103.910627 | −0.65839144 | 1.74E-08 | 6.96E-08 |
| GPT2 | 13.8115793 | 20.471803 | 0.56775987 | 1.90E-06 | 5.49E-06 |
| PSAT1 | 8.49768261 | 14.456719 | 0.7665988 | 2.20E-08 | 8.62E-08 |
| SLC7A5 | 9.6259589 | 4.77254443 | −1.01217164 | 7.78E-05 | 0.00016866 |
| ATF3 | 41.0233507 | 22.0827061 | −0.89352836 | 0.00017843 | 0.00036386 |
| TRIB3 | 6.07592407 | 11.0007963 | 0.85643221 | 2.52E-16 | 4.03E-15 |
| GDF15 | 21.0473355 | 144.794949 | 2.78230177 | 7.38E-15 | 7.67E-14 |
| HSD17B11 | 13.1829135 | 20.1501115 | 0.61211857 | 0.00319137 | 0.00535326 |
| FTL | 766.907965 | 1091.81751 | 0.50960638 | 5.73E-09 | 2.59E-08 |
| RPL8 | 395.640675 | 695.398594 | 0.8136494 | 5.30E-10 | 2.76E-09 |
| IL33 | 11.8544756 | 6.16193743 | −0.94397591 | 3.29E-11 | 2.01E-10 |
| SLC40A1 | 25.1349794 | 13.7589342 | −0.86932778 | 1.08E-12 | 8.33E-12 |
| HSPB1 | 306.167341 | 163.477643 | −0.90522705 | 5.78E-10 | 2.93E-09 |
| NFE2L2 | 19.1678795 | 12.8732042 | −0.57431956 | 2.86E-18 | 8.49E-17 |
| STEAP3 | 7.41152412 | 5.05498478 | −0.5520635 | 3.20E-12 | 2.38E-11 |
| ALOX15 | 2.40403468 | 3.70279423 | 0.62315667 | 5.40E-06 | 1.50E-05 |
| ACSF2 | 7.28389113 | 4.09436357 | −0.83107014 | 1.95E-18 | 6.77E-17 |
| NNMT | 6.2166145 | 10.0805857 | 0.69737844 | 0.00197336 | 0.0035082 |
| RRM2 | 2.39976615 | 3.47853334 | 0.53558532 | 4.52E-17 | 9.41E-16 |
| CAPG | 29.7087905 | 12.8672836 | −1.20718235 | 5.10E-18 | 1.33E-16 |
| FADS2 | 30.0348156 | 12.0841279 | −1.31352245 | 2.63E-11 | 1.66E-10 |
| TP63 | 11.47973 | 4.65738426 | −1.30149689 | 1.59E-21 | 3.31E-19 |
| CDKN1A | 36.5444473 | 25.0585009 | −0.5443521 | 0.00087592 | 0.00165629 |
| ACSL3 | 24.1737903 | 35.5872964 | 0.55791864 | 0.00161717 | 0.00289975 |
| CAV1 | 42.2752045 | 13.0398961 | −1.69687936 | 4.77E-20 | 2.70E-18 |
| DUOX1 | 6.81353266 | 3.15365595 | −1.11137772 | 1.43E-19 | 5.94E-18 |
| DUOX2 | 4.05444779 | 2.35413478 | −0.78430852 | 6.48E-16 | 8.99E-15 |
| ACSL4 | 7.44080417 | 4.40380152 | −0.7567091 | 4.00E-16 | 5.95E-15 |
| SAT1 | 90.4802257 | 157.613189 | 0.80071383 | 4.81E-07 | 1.63E-06 |
| ZEB1 | 6.18564437 | 4.00813542 | −0.62599264 | 8.33E-11 | 4.95E-10 |
| CDO1 | 17.8257701 | 5.84322985 | −1.60912646 | 2.99E-05 | 7.40E-05 |
| EPAS1 | 28.6465826 | 18.5812865 | −0.62451265 | 1.35E-08 | 5.60E-08 |
| ANO6 | 13.6183414 | 6.62211382 | −1.04018729 | 9.28E-21 | 9.65E-19 |