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BBD data displaying independent variables with their level of variation and the examined dependent variables.
| Independent Variable | Symbol | Level of Variation | ||
|---|---|---|---|---|
| Lowest (−1) |
Central (0) |
Highest (1) |
||
| Oil concentration (g) | X1 | 1.0 | 1.5 | 2.0 |
| Surfactant concentration (g) | X2 | 0.5 | 0.75 | 1.0 |
| Gelling agent concentration (g) | X3 | 0.8 | 1.0 | 1.2 |
| Dependent Variable | Symbol | Constraints | ||
| Viscosity (cP) | R1 | Minimize | ||
| In vitro release (%) | R2 | Maximize | ||
