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. 2021 Sep 1;188(1):540–559. doi: 10.1093/plphys/kiab420

Figure 9.

Figure 9

A proposed model of MdMIEL1–MdBBX7 module in apple drought stress response. When soil water is abundant, MdMIEL1 is accumulated. Accumulated MdMIEL1 then interacts with MdBBX7 and mediates the ubiquitination and degradation of MdBBX7 via the 26S protease pathway, thereby leading to the suppressed expression of target genes including MdERF1, MdGLK1, and MdERD15. Under drought stress conditions, MdMIEL1 is repressed, thereby resulting in accumulated MdBBX7. The accumulated MdBBX7 activates the expression of its downstream genes including MdERF1, MdGLK1, and MdERD15 by binding to the CCTTG or T/G box elements.