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Tumour microenvironment and novel potential biomarkers: sPDL1 = soluble PDL1; ctDNA = circulating tumour DNA; TGF-B = transforming growth factor beta; Trp = tryptophan; IDO = indoleamine 2,3-dioxygenase; Treg = regulatory T cell; Tex = exhausted T cell; MDSC = myeloid derived suppressor cell; Th1 = T helper cell Th1 subtype; Th9 = T helper cell Th9 subtype; IFNy = interferon gamma; IL-9 = interleukin 9; ICI = immune checkpoint inhibitor.
