Table 1.
Comparison of Allplex RP 1, 2, 3 and BioFire FilmArray RP assays for the detection of respiratory viruses in NPS specimens.
| Viruses | Allplex RP 1, 2, and 3 | BioFire FilmArray RP | ||
|---|---|---|---|---|
| Positive | Negative | Positive | Negative | |
| AdV | 31 (3) | 150 | 34 (5) | 147 |
| 229E | 0 | 181 | 0 | 181 |
| NL63 | 0 | 181 | 0 | 181 |
| OC43 | 0 | 181 | 0 | 181 |
| HKU1 | NT | NT | 0 | 181 |
| FluA | 2 | 179 | 2 | 179 |
| FluB | 0 | 181 | 0 | 181 |
| HBoV-1/2/3/4 | 10 | 171 | NT | NT |
| HEV/HRV a | 64 (25) | 117 | 39 | 142 |
| HEV | 24 (12) | 157 | NT | NT |
| HRV | 55 (26) | 126 | NT | NT |
| MPV | 0 | 181 | 0 | 181 |
| PIV-1 | 6 (3) | 175 | 4 (1) | 177 |
| PIV-2 | 5 (3) | 176 | 2 | 179 |
| PIV-3 | 5 (1) | 176 | 6 (2) | 175 |
| PIV-4 | 6 (4) | 175 | 2 | 179 |
| RSV-A/RSV-B b | 4 (1)/4 | 177/177 | 8 (1) | 173 |
| RSV-A | 4 (1) | 177 | NT | NT |
| RSV-B | 4 | 177 | NT | NT |
a: BioFire FilmArray RP assay does not differentiate between human enterovirus (HEV) and human rhinovirus (HRV) and reports them as a single analyte, HEV/HRV. b: BioFire FilmArray RP assay does not differentiate between RSV-A and RSV-B and reports them as a single analyte RSV-A/RSV-B. Numbers in parentheses indicate the analytes detected only by the one RP assay. NT: not tested. Abbreviations: AdV, adenovirus; 229E, NL63, and OC43, coronavirus; FluA, influenza A virus; FluB, influenza B virus; HBoV, human bocavirus 1/2/3/4; HEV, human enterovirus; MPV, human metapneumovirus; HRV, human rhinovirus; PIV-1, PIV-2, PIV-3, and PIV-4, parainfluenza viruses 1, 2, 3, and 4; RSV-A and RSV-B, respiratory syncytial virus A and B.