. 2022 Jan 20;17(1):e0262650. doi: 10.1371/journal.pone.0262650

Table 3. Differential expression of PD1 and CD39 on peripheral blood T lymphocytes among patients with triple-negative breast cancer and controls.

T lymphocyte subsets (%)	Patients (n = 30)	Controls (n = 20)	p- value
T lymphocytes	60.8±2	69.1±2	0.007
CD4⁺	40.1±1	51.3±1	<0.0001
CD8⁺	19.9±1	16.7±1	0.03
PD1⁺CD4⁺	30.9±3	11.6±0.6	<0.0001 ^a
PD1⁺CD8⁺	29.6±2	13.4±1	<0.0001 ^a
CD39⁺CD4⁺	18.3±2	8.1±1	<0.0001 ^a
CD39⁺CD8⁺	11.2±0.7	10.4±0.6	0.4^a

The percentages of the CD4⁺ and CD8⁺ cells were calculated within the T lymphocytes, and the percentages of PD-1⁺and CD39⁺ cells were assessed within each of the CD4⁺ and CD8⁺ T lymphocytes. Data expressed as mean ±SE, Independent samples t-test,

^a; Mann-Whitney test for significance, a p-value is significant if < 0.05.