Table 4. Differential expression of PD1 and CD39 among tumor-infiltrating and peripheral blood lymphocytes of patients with triple-negative breast cancer.
| T lymphocyte subsets (%) | Tissue lymphocytes | Peripheral lymphocytes | p-value |
|---|---|---|---|
| T lymphocytes | 26.6±0.9 | 60.8±2 | <0.0001 |
| CD4+ | 58.2±3 | 40.1±1 | <0.0001 |
| CD8+ | 34.2±3 | 19.9±1 | <0.0001 |
| PD1+CD4+ | 50.8 ± 4 | 30.9±3 | <0.0001 b |
| PD1+CD8+ | 34.9 ±2 | 29.6 ± 2 | 0.02 b |
| CD39+CD4+ | 21±2 | 18.3±2 | <0.0001 b |
| CD39+CD8+ | 13.6±0.9 | 11.2±0.7 | <0.0001 b |
The percentages of the CD4+ and CD8+cells were calculated within the T lymphocytes, and the percentages of PD-1+and CD39+cells were assessed within each of the CD4+ and CD8+ T lymphocytes. Data expressed as mean ±SE, independent sample t-test,
b; Wilcoxon signed ranks test, a p-value is significant if < 0.05.