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. Author manuscript; available in PMC: 2022 Jan 20.
Published in final edited form as: Mol Pharm. 2021 Sep 15;18(10):3871–3881. doi: 10.1021/acs.molpharmaceut.1c00531

Table 1.

Biodistribution of [18F]6 in Mice Bearing HepG2 Xenografts1

Organ 30 min 2 h 4 h
Liver 10.24 ± 2.51 2.14 ± 0.82 1.24 ± 0.82
Spleen 4.08 ± 1.04 0.79 ± 0.18 0.31 ± 0.04
Lungs 3.59 ± 0.90 0.81 ± 0.33 0.38 ± 0.12
Heart 3.52 ± 0.42 0.72 ± 0.16 0.26 ± 0.10
Kidneys 15.04 ± 2.66 2.54 ± 0.54 1.01 ± 0.33
Bladder 6.01 ± 5.14 2.55 ± 2.73 1.60 ± 1.96
Stomach 2.15 ± 0.80 1.72 ± 0.51 0.94 ± 0.26
Sm. Int. 9.46 ± 2.42 5.77 ± 2.59 1.89 ± 0.79
Lg. Int. 1.84 ± 0.43 16.28 ± 2.63 16.95 ± 1.45
Bone 1.58 ± 0.49 0.72 ± 0.13 0.65 ± 0.25
Muscle 2.43 ± 0.41 0.88 ± 0.18 0.39 ± 0.10
Blood 3.90 ± 0.70 0.83 ± 0.21 0.29 ± 0.12
Brain 0.84 ± 0.12 0.39 ± 0.15 0.16 ± 0.06
Tumor 3.80 ± 0.85 2.07 ± 0.41 0.98 ± 0.33
tumor/muscle 1.62 ± 0.55 2.46 ± 0.74 2.49 ± 0.58
tumor/blood 0.99 ± 0.22 2.66 ± 1.00 3.54 ± 1.25
tumor/liver 0.37 ± 0.03 1.09 ± 0.42 1.00 ± 0.52
1

Data presented as %ID/g