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. 2022 Jan 10;23(2):724. doi: 10.3390/ijms23020724

Table 5.

Characterization of the anticancer properties of TGS121.

Symbol Proposed Mechanism of Action Cell line IC50 Range (µM)
TGS121 Apoptosis induction,
inhibition of Ras-mediated pathway, cell cycle arrest at G2/M
Ras-3T3 0.231 ± 1.2
NIH3T3 5.05 ± 2.6