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Effects of CBX on astrocyte gap junctions and on astrocyte activity elicited by 4-AP: (A). Reduction in gap junction current between astrocytes (lower curve) by application of 300 µM CBX to the bath (see text). (B). Dose–response curve of the CBX effect on inter-astrocyte gap junctions, with error bars representing SD. (C). CBX at a 300 µM concentration simultaneously reduces astrocytic “epileptiform” activity elicited by 4-AP in two astrocytes in the hippocampal slice.
