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. 2022 Jan 10;23(2):739. doi: 10.3390/ijms23020739

Figure 5.

Figure 5

Main cellular pathways affected by GLP-1 in neurons. GLP-1R: GLP-1 receptor; cAMP: cyclic adenosine monophosphate; PKA: protein kinase A; MAPK: mitogen-associated protein kinase; CREB: cyclic adenosine monophosphate response element-binding protein; BAD: Bcl-2 antagonist of death; NFkB: nuclear factor-kappa B; PI3K: phosphoinositide 3-kinase; AKT: protein kinase B; mTOR: mammalian target of rapamycin; GSK-3B: glycogen synthase kinase 3 beta; FOXO1/03: forkhead box protein O1; ↓: decrease; ↑: increase; ∅ = impairment; +: plus.