Table 2.

Descriptive results of the biases found in the included clinical trials.

Study	Question Focus	Appropriate Randomization	Allocation Blinding	Double-Blind	Losses (<20%)	Prognostics or Demographic Characteristics	Outcomes	Intention to Treat Analysis	Sample Calculation	Adequate Follow-Up
Athauda et al. [9]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes
Athauda et al. [21]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes
Newsome et al. [18]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Nr	Yes
Armstrong et al. [23]	Yes	No	Yes	Yes	Nr	Yes	Yes	Yes	No	Yes
Armstrong et al. [22]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes
Bouchi et al. [24]	Yes	No	No	No	Yes	Yes	Yes	No	No	Yes
Khoo et al. [26]	Yes	Yes	No	No	NR	Yes	Yes	Yes	Nr	Yes
Smits et al. [29]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes
Petit et al. [28]	This study is not randomized. Therefore, COCHRANE guidelines do not apply here.
Khoo et al. [27]	Yes	Yes	No	No	Yes	Yes	Yes	Yes	Nr	Yes
Guo et al. [25]	Yes	Yes	No	No	Yes	Yes	Yes	No	Yes	Yes
Yan et al. [30]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes
Mullins et al. [17]	Yes	No	Yes	Yes	No	Yes	Yes	No	No	Yes
Gejl et al. [31]	Yes	No	Yes	Yes	Yes	Yes	Yes	No	No	Yes
Gejl et al. [32]	Yes	No	Yes	Yes	Yes	Yes	Yes	No	NR	Yes
Watson et al. [33]	Yes	Yes	Yes	Yes	No	Yes	Yes	No	No	Yes
Kahal et al. [35]	This study is not randomized. Therefore, COCHRANE guidelines do not apply here.
Moulton et al. [36]	This study is not randomized. Therefore, COCHRANE guidelines do not apply here.
Grant et al. [34]	This study is not randomized. Therefore, COCHRANE guidelines do not apply here.