SARS-CoV-1 |
Severe Acute Respiratory Syndrome Coronavirus-1 |
MERS-CoV |
Middle East Respiratory Syndrome Coronavirus |
SARS-CoV-2 |
Severe Acute Respiratory Syndrome Coronavirus-2 |
COVID-19 |
Coronavirus disease emerged in 2019 |
WHO |
World Health Organization |
ACE2 |
Angiotensin-Converting enzyme 2 |
MRI |
Magnetic Resonance Imaging |
NSAID |
Non-steroidal anti-inflammatory drug |
NO |
Nitric Oxide |
OA |
Osteoarthritis |
iNOS |
Inducible nitric oxide synthase |
COX-2 |
Cyclooxygenase 2 |
PGE2 |
Prostaglandin E2 |
RAS |
Renin-angiotensin system |
IL-6 |
Interleukin 6 |
IL-1β |
Interleukin 1 beta |
TNFα |
Tumor necrosis factor alfa |
SASP |
Senescence-associated secretory phenotype |
CCL2/3/4 |
C–C motif chemokine ligand 2/3/4 |
CXCL2 |
Chemokine (C-X-C motif) ligand 2 |
Peptide hormone EREG |
Protein encoded by EREG gene, epiregulin |
DRG |
Dorsal root ganglia |
AT1R |
Angiotensin II type 1 receptor |
PI3K |
Phosphoinositide 3-kinase |
MAPKs |
Mitogen-activated protein kinase |
JNK |
c-Jun N-terminal kinases |
ARB |
Angiotensin receptor blocker |
AT1R blocker |
Angiotensin II type I receptor blocker |
AT2R |
Angiotensin II type 2 receptor |
ACEI |
Angiotensin-converting enzyme inhibitor |
TMPRSS2 |
Transmembrane serine protease 2 |
Bmal1 |
Brain and muscle Arnt-like protein-1 |
Angiotensin (1–7)/MAS axis |
Angiotensin (1–7)/ mitochondrial assembly receptor axis |
COPD |
Chronic obstructive pulmonary disease |
nAchR |
Nicotinic acetylcholine receptor |
CHRNA7 |
Gene for the Cholinergic Receptor Nicotinic Alpha 7 Subunit |
α7nAchR |
Alfa7 nicotinic acetylcholine receptor |
CHRFAM7A |
human partial duplication of the CHRNA7 gene which encodes for the α7nAchR |