Table 1.

Basic information about main circadian clock proteins [22].

Protein Name	Gene Location on Chromosome	Size (Da)	Size (Amino Acids)	Circadian Clock Function
PER1	17p13.1	136,212	1290	repressor
PER2	2q37.3	136,579	1255	repressor
PER3	1p36.23	131,888	1201	repressor
Cry1	12q23.3	66,395	586	repressor
Cry2	11p11.2	66,947	593	repressor
BMAL1 (ARNTL)	11p15.3	68,762	626	activator
CLOCK	4q12	95,304	846	activator
RORα	15q22.2	58,975	523	regulator
REV-ERBα	17q21.1	66,805	614	regulator