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. 2022 Jan 20;17(1):e0262767. doi: 10.1371/journal.pone.0262767

Fig 5. LAB strains modulate TGF-β induced fibrogenic markers and SMAD-dependent TGF-β signaling in LX-2 cells.

Fig 5

Confluence LX-2 cells were treated with LABs for 48 h, and stimulated with TGF-β for 120 minutes. Western blot was performed to determine the level of α-SMA, Col1A1, p-SMAD2/3, and SMAD7 at the indicated time point. Image J software was used to determine the intensities of protein bands. The bar graphs are the average of two different experiments (mean + S.D). *p <0.05, ** p <0.01, ***p <0.001.