TABLE 2.
Factors associated with E. coli resistance to AMC as assessed by univariate analysis
| Risk factor | No. (%) of patientsa
|
OR (95% CI) | P value | |
|---|---|---|---|---|
| I-R | S value | |||
| Age>65 yr | 65 | 255 | ||
| No | 22 (33.9) | 105 (41.2) | 1 | |
| Yes | 43 (66.1) | 150 (58.8) | 1.37 (0.77–2.42) | 0.29 |
| Sex | 65 | 255 | ||
| Female | 49 (75.4) | 197 (77.3) | 1 | |
| Male | 16 (24.6) | 58 (22.7) | 1.11 (0.59–2.10) | 0.75 |
| Unit of hospitalization | 65 | 255 | ||
| AC | 43 (66.1) | 199 (78.0) | 1 | |
| IC | 12 (18.5) | 37 (14.5) | 1.50 (0.73–3.11) | 0.28 |
| LC | 10 (15.4) | 19 (7.5) | 2.44 (1.08–5.50) | 0.04 |
| Nosocomial acquisition | 65 | 255 | ||
| No | 48 (73.8) | 161 (63.1) | 1 | |
| Yes | 17 (26.2) | 94 (36.9) | 1.65 (0.89–3.02) | 0.11 |
| Urinary catheter | 64 | 255 | ||
| No | 47 (73.4) | 195 (76.5) | 1 | |
| Yes | 17 (26.6) | 60 (23.5) | 1.18 (0.63–2.20) | 0.62 |
| Prior (1 yr) hospitalization | 60 | 208 | ||
| No | 20 (33.3) | 109 (52.4) | 1 | |
| Yes | 40 (66.7) | 99 (47.6) | 2.20 (1.21–3.99) | 0.009 |
| Prior (1 yr) UTI | 60 | 208 | ||
| No | 26 (43.3) | 164 (78.8) | 1 | |
| Yes | 34 (56.7) | 44 (21.2) | 4.87 (2.72–8.73) | 0.001 |
| Prior (1 yr) urinary catheter | 62 | 208 | ||
| No | 33 (53.2) | 174 (83.7) | 1 | |
| Yes | 29 (46.8) | 34 (16.3) | 4.50 (2.48–8.14) | 0.001 |
| Prior (6 mo) antibiotic exposure | 65 | 255 | ||
| No | 32 (49.2) | 208 (81.6) | 1 | |
| Yes | 33 (50.8) | 47 (18.4) | 4.57 (2.62–7.94) | 0.001 |
a
I-R, intermediate and resistant strains; S, susceptible strains.