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. 2022 Jan 10;23(2):718. doi: 10.3390/ijms23020718
AD: Alzheimer’s disease
WT: wild type mouse expressing murine 4Rtau
mtWT: homozygous transgenic mouse knock-out for murine tau protein
hTau: homozygous transgenic mouse knock-out for murine tau protein and heterozygous expressing human forms of 3Rtau and 4Rtau proteins
3Rtau: tau with three repeats
4Rtau: tau with four repeats
β-actin; CK1-δ casein kinase δ
eIF2α eukaryotic initiation factor 2α
GSK β: glycogen synthase kinase 3β
IRE1: inositol-requiring enzyme 1α
LAMP1: lysosomal-associated membrane protein 3
LC3: microtubule-associated protein 1A/1B-light chain 3
MAP2: microtubule-associated protein 2
NFL: neurofilament light molecular weight
p38: p38-kinase
PHF1: anti-paired helical filament 1
PKAα/β: cAMP-dependent protein kinase A
SAPK/JNK: stress-activated protein kinase/Jun amino-terminal kinase
SRC: tyrosine-protein kinase SRC
Tau 5: monoclonal recognizing total tau protein
Tau AT8 monoclonal tau antibody phosphorylation sites Ser202/Thr305
Tau C3: tau truncated at aspartic acid 421
Tau MC1: conformation tau
Tau-N: nitrated tau
Tau-P: phosphorylated tau. The phosphorylation or nitration of the protein at the specific site is indicated in every case