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Tissue vascularity and oxygenation associated with SBRT or SBRT and immunotherapy. (a) Fold change in density of CD31+ endothelial cells in post-treatment relative to pre-treatment samples for dogs treated with SBRT or SBRT + immunotherapy (SBRT n = 6, SBRT and immunotherapy n = 5); (b) fold change in tumor hemoglobin saturation post-treatment relative to pre-treatment. (SBRT n = 3, SBRT and immunotherapy n = 2).
