Table 1.
Baseline characteristics of colorectal cancer cases and matched controls (193 pairs) in CLUE II, 1989
| Overall | Men | Women | ||||
|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | |
| N | 193 | 193 | 89 | 89 | 104 | 104 |
| Mean time from blood draw to cancer diagnosis (years) | 6.5 | 6.5 | 6.5 | |||
| Age (years), median (IQR) | 65 (54–71) | 65 (54–72) | 65 (57–70) | 65 (57–70) | 65.5 (53–72.5) | 65 (53–72) |
| BMI (kg/m2), median (IQR) | 25.8 (23.2–28.9) | 25.7 (23.6–28.5) | 26.5 (24.6–29.8) | 26.6 (23.7–28.7) | 25.5 (22.7–28.4) | 24.9 (23.2–27.5) |
| Female (%) | 53.9 | 53.9 | 100 | 100 | ||
| White (%) | 979 | 97.9 | 97.8 | 97.8 | 98.1 | 98.1 |
| CRC family history (%) | 7.8 | 2.6 | 4.5 | 2.2 | 10.6 | 2.9 |
| NSAID use (%) | 20.7 | 26.4 | 22.5 | 31.5 | 19.2 | 22.1 |
| Diabetes medication use (%) | 8.3 | 4.1 | 9.0 | 5.6 | 7.7 | 2.9 |
| HRT use (%) | 23.1 | 36.5 | ||||
| Smoking status (%) | ||||||
| Never | 48.7 | 52.3 | 32.6 | 39.3 | 62.5 | 63.5 |
| Current | 14.0 | 13.0 | 10.1 | 10.1 | 17.3 | 15.4 |
| Former | 37.3 | 34.7 | 57.3 | 50.6 | 20.2 | 21.2 |
| Alcohol intake (g/day)*, median (IQR) | 4.73 (1.65–11.52) | 5.87 (1.57–16.64) | 7.16 (1.57–33.54) | 6.33 (1.73–19.52) | 4.73 (1.65–10.11) | 1.96 (0.84–13.25) |
CRC colorectal cancer, HRT hormone replacement therapy
*
alcohol intake was assessed through FFQ that was available for 105 (54%) and 128 (66%) of CRC cases and controls