Table 1.

Evolution of metabolic syndrome diagnostic definitions throughout the years.

Clinical Measure	Criteria					Diagnosis
	Central Obesity	Blood Glc	High TG	Low HDL	High BP
AHA/ NHLBI (2009) [4]	WC >40” (men) or >35” (women)	IFG or on high blood Glc txt or T2DM dx	≥150 mg/dL or on TG txt	<40 mg/dL (men) or <50 mg/dL (women) or on HDL txt	≥130 mmHg systolic and/or ≥85 mmHg diastolic or on HTN txt	≥3 criteria
IDF (2005) [5,6]	WC >37” (men) or >32” (women) or BMI >30 kg/m2					≥3 criteria one of which should be central obesity
ATPIII (2001) [7]	WC >40” (men) or >35” (women)		≥150 mg/dL	<40 mg/dL (men) or <50 mg/dL (women)	≥130 mmHg systolic and ≥85 mmHg diastolic or on HTN txt	≥3 criteria
EGIR (1999) [8]	WC >37” (men) or >32” (women)	IFG or IGT		<39 mg/dL (men and women)	≥140 mmHg systolic and ≥90 mmHg diastolic or on HTN txt	≥3 criteria one of which should be IR *
WHO (1998) [1]	Waist/hip ratio > 0.9 (men) or > 0.85 (women) or BMI > 30 kg/m2	IFG orx IIGT or T2DM dx		<35 mg/dL (men) or <39 mg/dL (women)	≥140 mmHg systolic and ≥90 mmHg diastolic	≥3 criteria one of which should be IR **

Note that IFG is defined as ≥110 mg/dL in 2001 but this was momdified in 2004 to be ≥100 mg/dL, IGT is defined as 2 h glucose >140 mg/dL. * EGIR IR is defined as plasma insulin levels >75th percentile. ** WHO IR is defined as presence of IR or IFG or IGT. Abbreviations: AHA: American Heart Association, ATPIII: National Cholesterol Education Program Adult Treatment Panel III; dx: diagnosis; EGIR: European group for study of insulin resistance; Glc: glucose; HDL: high density lipoprotein; HTN: hypertension; IR: insulin resistance; IDF: International Diabetes Federation; IGT: impaired glucose tolerance; IFG: impaired fasting glucose; NHLBI: National Heart, Lung, and Blood Institute; TG: triglyceride; txt: treatment; WC: waist circumference; WHO: World Health Organization.