Table 3.
Age | N | %<LOD | AM | GM | (95% CI a) | P25 | P50 | P75 | P95 | |
---|---|---|---|---|---|---|---|---|---|---|
Whole Blood | ||||||||||
Metals | ||||||||||
Lead (ug·dL−1) | 12–18 | 912 | 2.74 | 0.883 | 0.802 | (0.754, 0.853) | 0.611 | 0.834 | 1.10 | 1.52 |
≥19 | 3747 | 0.1 | 1.79 | 1.60 | (1.56, 1.65) | 1.20 | 1.60 | 2.20 | 3.36 | |
Mercury (total) | 12–18 | 912 | 0 | 1.56 | 1.37 | (1.30, 1.43) | 1.00 | 1.35 | 1.84 | 3.02 |
≥19 | 3745 | 0 | 3.50 | 2.75 | (2.63, 2.88) | 1.75 | 2.71 | 4.15 | 8.81 | |
Spot Urine | ||||||||||
Metals | ||||||||||
Mercury (total) | 3–5 | 571 | 2.10 | 0.565 | 0.422 | (0.371, 0.479) | 0.257 | 0.396 | 0.693 | 1.30 |
6–11 | 887 | 1.24 | 0.581 | 0.394 | (0.370, 0.418) | 0.267 | 0.373 | 0.562 | 1.09 | |
12–18 | 906 | 3.31 | 0.577 | 0.413 | (0.374, 0.457) | 0.246 | 0.421 | 0.680 | 1.39 | |
≥19 | 3780 | 6.1 | 0.518 | 0.355 | (0.335, 0.376) | 0.196 | 0.339 | 0.616 | 1.42 | |
Cadmium | 3–5 | 571 | 18.7 | 0.160 | 0.108 | (0.086, 0.136) | 0.057 | 0.091 | 0.206 | 0.430 |
6–11 | 887 | 1.92 | 0.298 | 0.232 | (0.212, 0.255) | 0.146 | 0.231 | 0.354 | 0.735 | |
12–18 | 906 | 1.99 | 0.377 | 0.289 | (0.264, 0.316) | 0.182 | 0.297 | 0.445 | 0.951 | |
≥19 | 3781 | 6.8 | 0.615 | 0.359 | (0.326, 0.395) | 0.185 | 0.422 | 0.811 | 1.75 | |
Phthalates metabolites | ||||||||||
MEHHP | 3–5 | 571 | 0 | 45.9 | 34.6 | (31.3, 38.2) | 21.3 | 36.2 | 58.7 | 96.8 |
6–11 | 885 | 0 | 37.5 | 28.8 | (26.5, 31.2) | 18.7 | 29.6 | 47.2 | 85.3 | |
12–18 | 901 | 0.11 | 19.9 | 13.6 | (12.0, 15.5) | 8.39 | 14.8 | 24.6 | 53.6 | |
≥19 | 3781 | 0.4 | 23.1 | 13.2 | (12.0, 14.4) | 6.89 | 13.7 | 25.9 | 62.6 | |
MEOHP | 3–5 | 571 | 0 | 34.3 | 25.5 | (23.0, 28.3) | 15.2 | 26.2 | 40.9 | 83.6 |
6–11 | 885 | 0 | 25.7 | 19.2 | (17.6, 20.9) | 11.8 | 19.5 | 31.6 | 65.3 | |
12–18 | 901 | 0.22 | 14.1 | 9.24 | (8.02, 10.7) | 5.10 | 10.3 | 17.1 | 38.5 | |
≥19 | 3781 | 0.5 | 18.1 | 9.88 | (8.89, 11.0) | 5.03 | 10.7 | 20.8 | 50.9 | |
MECPP | 3–5 | 571 | 0 | 65.9 | 45.3 | (38.4, 53.5) | 25.6 | 46.7 | 80.9 | 173 |
6–11 | 885 | 0 | 59.0 | 44.5 | (40.9, 48.5) | 27.2 | 44.0 | 72.6 | 144 | |
12–18 | 901 | 0 | 36.8 | 28.4 | (25.3, 31.8) | 18.0 | 28.5 | 45.7 | 89.7 | |
≥19 | 3781 | 0 | 40.3 | 23.2 | (20.8, 25.7) | 11.4 | 21.7 | 44.0 | 131 | |
MnBP | 3–5 | 571 | 0.53 | 79.8 | 47.2 | (40.8, 54.6) | 32.2 | 52.9 | 79.1 | 157 |
6–11 | 885 | 0 | 55.9 | 43.2 | (40.6, 46.1) | 28.3 | 45.1 | 68.8 | 126 | |
12–18 | 897 | 0.11 | 60.6 | 36.9 | (29.6, 46.0) | 18.6 | 36.5 | 76.8 | 168 | |
≥19 | 3779 | 1.1 | 45.6 | 22.3 | (19.2, 25.8) | 12.5 | 25.3 | 52.0 | 125 | |
MBzP | 3–5 | 571 | 3.68 | 8.06 | 3.12 | (2.65, 3.69) | 1.62 | 3.21 | 6.83 | 22.0 |
6–11 | 885 | 5.99 | 6.85 | 2.80 | (2.34, 3.35) | 1.35 | 3.17 | 7.02 | 24.2 | |
12–18 | 901 | 3.77 | 6.91 | 2.78 | (2.36, 3.27) | 1.19 | 2.97 | 6.90 | 25.3 | |
≥19 | 3781 | 2.0 | 4.40 | 1.99 | (1.80, 2.20) | 0.932 | 2.05 | 4.30 | 14.6 | |
MCNP | 3–5 | 571 | 4.90 | 0.670 | 0.491 | (0.425, 0.568) | 0.316 | 0.464 | 0.685 | 1.83 |
6–11 | 885 | 2.26 | 0.661 | 0.533 | (0.505, 0.562) | 0.408 | 0.526 | 0.674 | 1.45 | |
12–18 | 901 | 3.11 | 0.535 | 0.452 | (0.423, 0.483) | 0.331 | 0.499 | 0.594 | 1.02 | |
≥19 | 3781 | 10.5 | 0.613 | 0.441 | (0.395, 0.493) | 0.228 | 0.502 | 0.774 | 1.47 | |
MCOP | 3–5 | 571 | 0 | 2.27 | 1.62 | (1.43, 1.83) | 0.894 | 1.55 | 2.66 | 6.76 |
6–11 | 885 | 0.11 | 3.38 | 2.24 | (2.07, 2.42) | 1.28 | 2.13 | 3.79 | 8.31 | |
12–18 | 901 | 1.89 | 2.41 | 1.71 | (1.55, 1.88) | 1.07 | 1.73 | 2.94 | 6.83 | |
≥19 | 3781 | 0.6 | 1.74 | 1.07 | (0.968, 1.19) | 0.569 | 1.06 | 1.95 | 4.59 | |
MCPP | 3–5 | 571 | 0.18 | 2.28 | 1.80 | (1.63, 1.99) | 1.25 | 1.70 | 2.57 | 5.30 |
6–11 | 885 | 0.45 | 1.97 | 1.56 | (1.49, 1.64) | 1.07 | 1.45 | 2.08 | 4.43 | |
12–18 | 901 | 0.22 | 1.75 | 1.48 | (1.35, 1.62) | 1.03 | 1.38 | 2.09 | 3.89 | |
≥19 | 3781 | 0.6 | 1.63 | 1.13 | (1.02, 1.25) | 0.672 | 0.997 | 2.02 | 3.84 | |
Environmental phenols | ||||||||||
Bisphenol A | 3–5 | 571 | 1.23 | 4.33 | 2.41 | (2.05, 2.83) | 1.43 | 2.60 | 4.39 | 10.6 |
6–11 | 887 | 3.95 | 3.22 | 1.70 | (1.49, 1.95) | 0.849 | 1.98 | 3.59 | 10.1 | |
12–18 | 904 | 3.10 | 2.65 | 1.39 | (1.20, 1.61) | 0.755 | 1.45 | 2.84 | 9.13 | |
≥19 | 3780 | 2.1 | 2.51 | 1.18 | (1.06, 1.32) | 0.517 | 1.32 | 2.76 | 7.78 | |
Bisphenol F | 3–5 | 571 | 69.9 | * | * | * | <LOD | <LOD | 0.093 | 0.761 |
6–11 | 884 | 65.3 | * | * | * | <LOD | <LOD | 0.132 | 1.20 | |
12–18 | 900 | 56.0 | * | * | * | <LOD | <LOD | 0.153 | 1.48 | |
≥19 | 3777 | 59.3 | * | * | * | <LOD | <LOD | 0.141 | 1.23 | |
Bisphenol S | 3–5 | 571 | 47.5 | * | * | * | <LOD | 0.020 | 0.046 | 0.186 |
6–11 | 884 | 46.0 | * | * | * | <LOD | 0.023 | 0.065 | 0.523 | |
12–18 | 900 | 38.2 | 0.293 | 0.053 | (0.041, 0.068) | <LOD | 0.036 | 0.120 | 1.08 | |
≥19 | 3776 | 45.7 | * | * | * | <LOD | 0.022 | 0.057 | 0.288 | |
Triclosan | 3–5 | 571 | 21.9 | 1.57 | 0.513 | (0.435, 0.606) | 0.208 | 0.400 | 1.02 | 4.79 |
6–11 | 887 | 32.6 | 3.52 | 0.452 | (0.404, 0.507) | <LOD | 0.316 | 0.828 | 6.05 | |
12–18 | 904 | 35.3 | 3.96 | 0.420 | (0.369, 0.479) | <LOD | 0.315 | 0.714 | 4.75 | |
≥19 | 3780 | 50.9 | * | * | * | <LOD | <LOD | 0.538 | 5.39 | |
Methyl Paraben | 3–5 | 571 | 0 | 646 | 46.3 | (37.1, 57.8) | 8.81 | 25.8 | 150 | 3445 |
6–11 | 884 | 0 | 188 | 28.9 | (24.6, 33.9) | 7.16 | 18.8 | 91.3 | 913 | |
12–18 | 900 | 0 | 107 | 26.1 | (21.9, 31.2) | 7.17 | 18.2 | 91.5 | 510 | |
≥19 | 3779 | 0 | 128 | 35.2 | (32.0, 38.6) | 9.26 | 34.6 | 126 | 506 | |
Ethyl Paraben | 3–5 | 571 | 1.05 | 106 | 14.2 | (10.5, 19.1) | 2.66 | 17.2 | 66.2 | 526 |
6–11 | 884 | 1.13 | 122 | 11.4 | (8.56, 15.3) | 1.96 | 10.6 | 69.0 | 504 | |
12–18 | 900 | 0.44 | 85.6 | 19.1 | (14.0, 26.2) | 4.88 | 19.0 | 71.6 | 350 | |
≥19 | 3779 | 1.0 | 158 | 30.9 | (27.1, 35.2) | 7.82 | 36.2 | 139 | 676 | |
Propyl Paraben | 3–5 | 571 | 0.70 | 153 | 4.36 | (3.29, 5.80) | 0.664 | 2.48 | 18.0 | 699 |
6–11 | 884 | 5.43 | 30.7 | 1.83 | (1.52, 2.21) | 0.346 | 1.37 | 7.15 | 104 | |
12–18 | 900 | 2.11 | 38.7 | 3.19 | (2.55, 3.98) | 0.796 | 2.11 | 10.8 | 212 | |
≥19 | 3778 | 3.9 | 51.0 | 3.07 | (2.73, 3.46) | 0.464 | 2.12 | 16.9 | 224 | |
Pyrethroid pesticides metabolites | ||||||||||
3-PBA | 3–5 | 570 | 0.35 | 2.24 | 1.08 | (0.870, 1.33) | 0.536 | 0.970 | 1.86 | 9.34 |
6–11 | 887 | 0.68 | 2.40 | 1.36 | (1.21, 1.52) | 0.749 | 1.29 | 2.39 | 7.44 | |
12–18 | 904 | 1.66 | 2.03 | 1.02 | (0.842, 1.24) | 0.565 | 1.12 | 2.18 | 5.93 | |
≥19 | 3772 | 0.9 | 1.82 | 0.965 | (0.887, 1.05) | 0.499 | 1.03 | 2.05 | 6.09 | |
Environmental tobacco smoke metabolites | ||||||||||
Cotinine | 3–5 | 571 | 20.5 | 1.69 | 1.05 | (0.913, 1.20) | 0.450 | 1.19 | 2.29 | 4.80 |
6–11 | 887 | 18.9 | 2.12 | 1.20 | (1.05, 1.38) | 0.521 | 1.48 | 2.82 | 5.84 | |
12–18 | 904 | 7.19 | 36.1 | 3.04 | (2.50, 3.70) | 1.40 | 2.79 | 4.72 | 85.2 | |
≥19 | 3784 | 6.7 | 240 | 5.59 | (4.80, 6.50) | 0.799 | 1.80 | 12.7 | 1530 | |
19 years and older | None | 3181 | 84.0 | 39.6 | 1.87 | (1.65, 2.12) | 0.698 | 1.30 | 3.10 | 75.6 |
Smoker | 603 | 16.0 | 1071 | 524 | (393, 700) | 429 | 1008 | 1504 | 2575 | |
PAHs metabolites | ||||||||||
1-OH-Pyr | 3–5 | 554 | 47.5 | * | * | * | <LOD | 0.080 | 0.353 | 1.02 |
6–11 | 864 | 34.4 | 0.319 | 0.108 | (0.091, 0.127) | <LOD | 0.208 | 0.442 | 1.02 | |
12–18 | 867 | 31.5 | 0.613 | 0.163 | (0.115, 0.230) | <LOD | 0.338 | 0.804 | 2.21 | |
≥19 | 3754 | 28.4 | 0.364 | 0.130 | (0.118, 0.143) | <LOD | 0.201 | 0.434 | 1.28 | |
2-NAP | 3–5 | 554 | 1.26 | 6.30 | 3.37 | (2.89, 3.92) | 1.64 | 3.31 | 7.16 | 21.3 |
6–11 | 864 | 3.82 | 5.63 | 2.67 | (2.37, 3.01) | 1.45 | 2.71 | 5.16 | 19.8 | |
12–18 | 866 | 2.77 | 6.29 | 3.05 | (2.63, 3.53) | 1.69 | 3.15 | 6.40 | 20.2 | |
≥19 | 3754 | 1.3 | 5.59 | 2.63 | (2.48, 2.79) | 1.23 | 2.42 | 6.16 | 21.0 | |
1-OH-Phe | 3–5 | 554 | 38.3 | 0.156 | 0.080 | (0.069, 0.093) | <LOD | 0.054 | 0.194 | 0.499 |
6–11 | 864 | 41.8 | * | * | * | <LOD | 0.168 | 0.360 | 0.933 | |
12–18 | 866 | 38.2 | 0.265 | 0.127 | (0.107, 0.151) | <LOD | 0.158 | 0.367 | 0.822 | |
≥19 | 3751 | 32.5 | 0.269 | 0.117 | (0.109, 0.126) | <LOD | 0.135 | 0.303 | 0.779 | |
2-OH-Flu | 3–5 | 549 | 19.7 | 2.18 | 0.495 | (0.327, 0.750) | 0.133 | 0.589 | 1.98 | 10.7 |
6–11 | 864 | 20.0 | 0.380 | 0.209 | (0.178, 0.246) | 0.085 | 0.279 | 0.513 | 1.08 | |
12–18 | 867 | 15.9 | 0.485 | 0.263 | (0.225, 0.307) | 0.145 | 0.317 | 0.647 | 1.40 | |
≥19 | 3754 | 14.1 | 0.697 | 0.321 | (0.295, 0.349) | 0.159 | 0.379 | 0.780 | 2.58 | |
VOCs metabolites | ||||||||||
t,t-MA | 3–5 | 571 | 0 | 133 | 82.2 | (71.9, 94.1) | 41.7 | 73.2 | 148 | 470 |
6–11 | 887 | 0.56 | 161 | 91.2 | (81.9, 101) | 45.9 | 86.1 | 177 | 457 | |
12–18 | 904 | 0.66 | 147 | 80.4 | (68.1, 95.0) | 42.6 | 82.9 | 156 | 441 | |
≥19 | 3777 | 0.4 | 162 | 86.2 | (80.7, 92.0) | 41.4 | 88.5 | 185 | 498 | |
BMA | 3–5 | 571 | 0 | 26.9 | 10.6 | (9.31, 12.2) | 5.58 | 9.27 | 17.6 | 120 |
6–11 | 883 | 0 | 13.1 | 7.39 | (6.69, 8.16) | 4.08 | 6.90 | 11.6 | 36.7 | |
12–18 | 899 | 0.33 | 9.09 | 5.66 | (5.00, 6.40) | 3.29 | 6.04 | 9.71 | 27.1 | |
≥19 | 3777 | 0.4 | 11.8 | 4.63 | (4.28, 5.02) | 2.42 | 4.74 | 8.95 | 27.9 |
a 95% confidence interval of the GM; GM, geometric mean; * 40% of samples were below the LOD, so the percentile distribution was reported, but GM was not calculated; LOD, limit of detection; AM, arithmetic mean.