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Editing profiles of HeLa cells with impaired repair pathways. Bar plots for the frequency of deletions (A) and insertions (B). Indel lengths are shown following DNA repair of TALEN-induced DNA damage. For each sample, we measured between 42,733 and 64,104 deletion and 19,598 and 25,620 insertion editing events. (C) Ratio of deletion to insertion Indels for HeLa cells with impaired repair pathways. Standard errors reflect duplicate measurements. The color key is in panel A.
