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Enzymatic activity of selected avermectins against the purified M. smegmatis DprE1. 1 BTZ data was obtained from reference [25].
| Avermectin | IC50 (µM) |
|---|---|
| Ivermectin | 13.2 ± 3.3 |
| Milbemycin oxime | 25.5 ± 5.6 |
| Moxidectin | 6.1 ± 0.9 |
| Selamectin | 2.6 ± 1.1 |
| BTZ-043 1 | 0.004 |
