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. 2022 Jan 10;60(2):16. doi: 10.3892/ijo.2022.5306

Table III.

Gene Ontology pathways and gene networks through which PDIA1 confers anti-carcinogenic effects to patients with ERα-positive breast cancer.

Term Description Hits Log P Log (q-value)
1 GO:0031589 Cell-substrate adhesion SMAD6 −6.61 −2.26
2 GO:0040008 Regulation of growth PTPRS, TKT −3.93 −0.48
3 GO:0000302 Response to reactive oxygen species PYCR1, PRDX2, UCP2 −3.98 −0.48

SMAD6, SMAD family member 6; PTPRS, protein tyrosine phosphatase receptor type S; TKT, transketolase; PYCR1, pyrroline-5-carboxylate reductase 1; PRDX2, peroxiredoxin 2; UCP2, uncoupling protein 2.