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The effects of combined treatment (FUS+GAS) on the level of Aβ (a, b), tau (c, d), and P-tau (e, f) in the left hippocampus. The content of Aβ was increased markedly in the untreated group. Combined treatment reduced the content of Aβ, tau, and P-tau in the targeted hippocampus. Each symbol represents the mean ± SD; ∗P < 0.05 against untreated mice. One-way ANOVA; n = 5 per group.
