Table 1.
Effects of caffeic acid (CA) against atherogenic diet- (Ath-) induced alteration(s) in blood biochemistry.
| Group | Cholesterol (mg/dL) | HDL (mg/dL) | LDL (mg/dL) | VLDL (mg/dL) | TG (mg/dL) | LDH (IU/L) | ALT (IU/L) | AST (IU/L) | AIP |
|---|---|---|---|---|---|---|---|---|---|
| Control | 157.2 ± 1.515 | 65.17 ± 0.307 | 74.16 ± 0.477 | 30.17 ± 0.477 | 120.1 ± 0.167 | 130.1 ± 0.307 | 80.5 ± 0.428 | 9 ± 0.365 | 1.6 ± 1.141 |
| Ath control | 321.5 ± 2.861a | 25.17 ± 0.307a | 212.3 ± 0.615a | 62.5 ± 0.563a | 346 ± 0.365a | 345.3 ± 0.307a | 131 ± 0.365a | 51.33 ± 0.365a | 10.7 ± 0.23a |
| Ath + CA (25 mg/kg) | 238.5 ± 3.442z | 35.0 ± 0.3651z | 139.8 ± 0.477z | 42.5 ± 0.428z | 250.83 ± 0.307z | 236.5 ± 0.31z | 119.16 ± 0.494z | 31 ± 0.516z | 5.4 ± 1.374z |
| Ath + CA (50 mg/kg) | 187.2 ± 2.926z | 48.5 ± 0.2236z | 109.6 ± 0.558z | 37 ± 0.447z | 160.8 ± 0.401z | 191.8 ± 0.308z | 97.83 ± 0.365z | 22 ± 0.364z | 3.13 ± 1.137z |
| Control + CA (50 mg/kg) | 157.8 ± 2.428 | 67.0 ± 0.333 | 70.8 ± 0.428 | 28.5 ± 0.429 | 119.6 ± 0.494 | 128 ± 0.365 | 78 ± 0.365 | 7 ± 0.966 | 1.4 ± 1.031 |
| Ath + ATORVA (5) | 131.7 ± 2.076z | 48.0 ± 0.365z | 92.5 ± 0.5z | 33.6 ± 0.333z | 131.1 ± 0.307z | 161 ± 0.365z | 88.3 ± 0.364z | 18.1 ± 0.477z | 2.5 ± 0.118z |
Values are expressed as mean ± S.E.M. ap < 0.001vs. the control group, zp < 0.001vs. the Ath control group. Data are analyzed using one-way ANOVA followed by Tukey's HSD post hoc test. HDL : high-density lipoprotein, LDL : low-density lipoprotein, VLDL : very-low-density lipoprotein, TG : triglyceride, AIP : atherogenic index in plasma.