. 2022 Jan 13;2022:4524032. doi: 10.1155/2022/4524032

Table 2.

Associations between PhenoAge, PhenoAgeAccel, and all-cause mortality on follow-up.

Variable	HR (95% CI)
Variable	Model 1^a	Model 2^b	Model 3^c
PhenoAge (per year)	1.05 (1.02, 1.08)^∗∗∗	1.06 (1.03, 1.09)^∗∗∗	1.04 (1.01, 1.08)^∗
PhenoAge (per 10 years)	1.63 (1.27, 2.11)^∗∗∗	1.74 (1.34, 2.27)^∗∗∗	1.51 (1.10, 2.08)^∗
PhenoAgeAccel subgroups
Negative	Reference	Reference	Reference
Positive	2.29 (1.38, 3.81)^∗∗	2.58 (1.51, 4.41)^∗∗	2.08 (1.14, 3.80)^∗

Results are based on COX regression analysis. HR: hazard ratio; PhenoAge: phenotypic age; PhenoAgeAccel: phenotypic age acceleration. ^aModel 1 adjusted for chronological age. ^bModel 2 additionally adjusted for lesion number, disease count, and revascularization. ^cModel 3 additionally adjusted for other traditional cardiovascular risk factors, including gender, smoking, drinking, body mass index, serum uric acid, creatine kinase, creatine phosphokinase isoenzyme, total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and N-terminal probrain natriuretic peptide. ⁺P < 0.1; ^∗P < 0.05; ^∗∗P < 0.01; ^∗∗∗P < 0.001.