Table 1.
Clinical and demographical characteristics of the studied cohort of patients.
| Death(38) | Hospital discharge(27) | Covalescent plasmaDonor(62) | Controls(37) | p-value | |
|---|---|---|---|---|---|
| Gender (male) | 23 (60.5%) |
13 (48.1%) |
33 (53.2%) |
17 (45.9%) |
0.607 |
| Age | 57.37 ± 14.891 |
50.63 ± 17.6 | 36.18 ± 10.5 |
50 ± 18.38 |
< 0.001 |
| FY c.-67T>C | 0.079 | ||||
| W/W | 24 (63.2%) | 17 (63%) |
52 (83.9%) |
31 (83.8%) |
|
| W/M | 10 (26.3%) |
8 (29.6%) |
5 (8.05%) |
4 (10.8%) |
|
| M/M | 4 (10.5%) |
2 (7.4%) |
5 (8.05%) |
2 (5.4%) |
|
| Grouped c.-67T>C genotype | |||||
| Only wild alleles | 24 (63.2%) |
17 (63%) |
52 (83.9%) |
31 (83.8%) |
0.027 |
| One or more mutated alleles | 14 (36.8%) |
10 (37%) |
10 (16.1%) |
6 (16.2%) |
|
| Hypertension (yes/no) | 11 (37.9%)/ 18 (62.1%) |
11 (52.4%)/ 10 (47.6%) |
3 (4.8%)/ 59 (95.2%) |
- | <0.001 |
| Diabetes (yes/no) | 9 (31%)/ 20 (69%) |
3 (14.3%)/ 18 (85.7%) |
0 (0%)/ 62 (100%) |
- | <0.001 |
| Self-declared race | |||||
| Caucasian | 28 (73.7%) |
17 (65.4%) |
47 (75.8%) |
28 (75.7%) |
0.509 |
| African | 10 (26.3%) |
9 (34.6%) |
12 (19.4%) |
8 (21.6%) |
|
| Other | 0 | 0 | 3 (4.8%) |
1 (2.7%) |