Table 1. Summary of some of the central peptides changes in AN.

AN: Anorexia nervosa; CSF: Cerebrospinal fluid; ND: No difference from healthy controls; Increased: Higher than healthy controls; Decreased: Lower than healthy controls; AGRP: Agouti-related peptide; BDNF: Brain-derived neurotrophic factor; CRH: Corticotropin-releasing hormone; TRH: Thyrotropin-releasing hormone; SRIF: Somatostatin; α-MSH: α-melanocyte-stimulating hormone; NPY: Neuropeptide Y

	Changes in AN		Reference
	Acute Phase (AN)	Weight restored (AN)
Plasma AGRP	Increased	No Difference	Merle et al. (2011)       [33]
Serum BDNF                                                                                                                                                            Plasma BDNF	Decreased               Increased	Decreased	Brandys et al. (2011) [34]
CSF CRH	Increased	Increased	Hotta et al. (1986) [35]
Plasma Oxytocin	Decreased	ND	Lawson et al. (2012) [36]
CSF TRH	Decreased	Decreased	Lesem et al. (1994) [37]
CSF SRIF                                                                                                                                         Plasma SRIF	Decreased           Increased	ND	Kaye et al. (1988) [38]
Plasma α-MSH	ND	ND	Moriya et al. [39]
CSF NPY                                                                                                                                                 Plasma NPY	Increased                 ND	Increased                                                              ND	Sedlackova et al. (2011) [40]
CSF Vasopressin                                                                                                                           Plasma Vasopressin	ND/Decreased  ND/Decreased	ND/Decreased                                  ND/Decreased	Gold et al. (1983) [41]