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. 2022 Jan 21;181(5):1933–1942. doi: 10.1007/s00431-021-04358-8

Table 2.

Clinical features of neonates with RT-PCR proven SARS-CoV-2 infection and admitted to hospital

Complaints n (%)
Asymptomatic 19 (10.8)
Fever 113 (64.2)
  Only fever 45 (25.6)
  + Any respiratory symptoms 23 (13.1)
  + Any GIS symptoms 23 (13.1)
  + Respiratory and GIS symptoms 11 (6.2)
  + Somnolence/irritability 5 (2.8)
Feeding intolerance 45 (25.6)
Cough 38 (21.6)
Tachypnea 33 (18.8)
Retractions 22 (12.5)
Diarrhea 14 (8)
Rhinorrhea 14 (8)
Somnolence/Irritability 13 (7.4)
Rash 3 (1.7)
Hospitalization (n, %) 170 (96.6)
Chest CT (n, %) 8 (4.5)
  Groundglass/consolidation 4 (2.2)
Complications
  Myocarditis (n, %) 10 (5.7)
  DIC (n, %) 1 (0.6)
  Multiple organ dysfunction (n, %) 1 (0.6)
Feeding type
  Breastfeeding with PPE (n, %) 31 (17.6)
  Expressed milk with PPE (n, %) 90 (51.1)
  Breastfeeding without PPE (n, %) 13 (7.4)
  Formula (n, %) 42 (23.9)
Treatment Duration (median, min–max)
  No treatment (n, %) 69 (39.2)
  Antibiotic treatment (n, %) (days) 95 (54) 7 (2–26)
  Azithromycin treatment (n, %), (days) 29 (16.5) 5 (1–10)
  Oseltamivir treatment (n, %), (days) 15 (8.5) 5 (5–7)
Respiratory support
  Oxygen supplementation (n, %) (h) 47 (26.7) 58 (8–504)
  nCPAP requirement (n, %) (h) 17 (9.6) 47 (6–456)
  Mechanical ventilation (n, %) (h) 8 (4.5) 47.5 (5–494)
Hospitalization (days) 9 (1–70)

GIS gastrointestinal system, CT computed tomography, DICdisseminated intravascular coagulation, PPE personal protective equipment, nCPAP nasal continuous airway pressure