Table 1.
Participant characteristics.
| Characteristic | All Participants | No Report of Exposed Bone | Any Report of Exposed Bone | P-value |
|---|---|---|---|---|
| n | 572 | 537 | 35 | |
| Age (SD) | 58.3 (11.1) | 58.3 (11.2) | 57.7 (8.9) | 0.74 |
| Male | 440 (76.9%) | 411 (76.4%) | 29 (82.9%) | 0.53 |
| Race* | 0.086 | |||
| White | 474 (84.9%) | 446 (85.0%) | 28 (84.9%) | |
| African American | 45 (8.1%) | 40 (7.6%) | 5 (15.2%) | |
| Other | 39 (7.0%) | 39 (7.4%) | 0 (0%) | |
| Hispanic | 29 (5.1%) | 27 (5.0%) | 2 (5.7%) | 0.70 |
| Primary RT site¶ | 0.087 | |||
| Oropharynx | 262 (49.2%) | 247 (49.6%) | 15 (42.9%) | |
| Oral Cavity | 82 (15.4%) | 71 (14.3%) | 11 (31.4%) | |
| Salivary Gland | 54 (10.1%) | 53 (10.6%) | 1 (2.9%) | |
| Larynx/Hypopharynx | 40 (7.5%) | 37 (7.4%) | 3 (8.6%) | |
| Other | 95 (17.8%) | 90 (18.0%) | 5 (14.3%) | |
| Definitive RT¶¶ | 219 (41.1%) | 204 (40.6%) | 15 (46.9%) | 0.58 |
| RT type | 0.76 | |||
| IMRT | 538 (94.1%) | 504 (93.9%) | 34 (97.1%) | |
| Proton | 31 (5.4%) | 30 (5.6%) | 1 (2.9%) | |
| Other or missing | 3 (0.5%) | 3 (0.6%) | 0 (0.0%) | |
| Total RT dose in cGy to primary site (SD)** | 6573 (663) | 6560 (674) | 6773 (399) | 0.065 |
| Received chemotherapy (chemoRT) | 364 (63.6%) | 340 (63.3%) | 24 (68.6%) | 0.59 |
| BL status*** | 0.008 | |||
| Extraction | 182 (31.8%) | 163 (30.4%) | 19 (54.3%) | |
| Hopeless | 24 (4.2%) | 22 (4.1%) | 2 (5.7%) | |
| No extraction or hopeless | 366 (64.0%) | 352 (65.5%) | 14 (40.0%) | |
| BL n teeth (SD)**** | 22.9 (5.8) | 23.0 (5.7) | 21.3 (6.5) | 0.090 |
| Dental Insurance | 366 (64.0%) | 345 (64.2%) | 21 (60.0%) | 0.59 |
| Checkup last year | 414 (72.4%) | 393 (73.2%) | 21 (60.0%) | 0.12 |
| Education > High Schoolß | 412 (72.3%) | 390 (72.9%) | 22 (62.9%) | 0.24 |
| Brush/floss§ | 242 (42.3%) | 226 (42.1%) | 16 (45.7%) | 0.73 |
| Fluoride§ | 156 (27.4%) | 150 (28.0%) | 6 (17.7%) | 0.24 |
| WMA PD (SD)§§ | 2.35 (0.52) | 2.34 (0.51) | 2.51 (0.53) | 0.091 |
| % sites PD≥5 (SD) | 3.0 (6.0) | 2.9 (5.8) | 5.0 (8.5) | 0.055 |
| % sites PD≥4 (SD) | 11.1 (13.0) | 10.9 (12.8) | 14.2 (14.8) | 0.18 |
| WMA CAL (SD) | 1.92 (0.99) | 1.90 (0.99) | 2.20 (0.97) | 0.11 |
| % sites CAL≥3 (SD) | 27.8 (25.2) | 27.5 (25.2) | 33.3 (26.3) | 0.22 |
| % sites CAL≥2 (SD) | 53.1 (27.1) | 52.6 (27.2) | 61.1 (23.0) | 0.097 |
n = 558, 525 for “none”, 33 for “any”; 14 answered “Don’t know/decline to state”. “Other" includes people who selected more than one race.
n = 533, n = 498 for “none”, 35 for “any”; the other 39 had “Other” or “Don’t know”.
n = 534 for definitive vs. adjuvant post-surgical
n = 571, n = 536 for “none”, 35 for “any”; the other 1 had missing data.
Had an extraction at BL vs. had no extractions but had a tooth declared hopeless vs. had no teeth extracted or declared hopeless.
n = 571, n = 536 for “none”, 35 for “any”; the other 1 had missing data.
n = 570, n = 535 for “none”, 35 for “any”; 2 declined to state.
Brush/floss: Reported brushing at least 2x daily and flossing at least daily; Fluoride: reporting using prescription fluoride at least daily. Fluoride compliance n = 569, n = 535 for “none”, 34 for “any”.
WMA = “whole mouth average”; n = 533 for BL periodontal data; n = 503 for “none”, 30 for “any”. The other 39 did not have periodontal measures taken, almost all because they would have required antibiotic prophylaxis.
RT = radiation therapy; IMRT = intensity modulated radiation therapy; BL = baseline.