Table 5.
Stage | Time (min) | Vehicle | L-NAME |
---|---|---|---|
| |||
Pre | −15 | 37.5 ± 0.1 | 37.4 ± 0.1 |
0 | 37.4 ± 0.1 | 37.4 ± 0.1 | |
Average | 37.5 ± 0.1 | 37.4 ± 0.1 | |
Post-vehicle or L-NAME | +5 | 37.6 ± 0.1 | 37.5 ± 0.1 |
+10 | 37.5 ± 0.1 | 37.5 ± 0.1 | |
+15 | 37.4 ± 0.1 | 37.3 ± 0.1 | |
Post-fentanyl | +5 | 37.5 ± 0.1 | 37.4 ± 0.1 |
+10 | 37.6 ± 0.1 | 37.4 ± 0.1 | |
+15 | 37.5 ± 0.1 | 37.3 ± 0.1 | |
+30 | 37.7 ± 0.1 | 37.6 ± 0.2 | |
+45 | 37.7 ± 0.2 | 37.6 ± 0.2 | |
+60 | 37.9 ± 0.2 | 37.8 ± 0.1 | |
| |||
Arithmetic changes from the average pre value | |||
| |||
Post-vehicle or L-NAME | +5 | +0.1 ± 0.1 | +0.0 ± 0.1 |
+10 | 0.0 ± 0.1 | +0.0 ± 0.1 | |
+15 | 0.0 ± 0.1 | −0.0 ± 0.1 | |
Post-fentanyl | +5 | 0.0 ± 0.1 | +0.0 ± 0.1 |
+10 | +0.1 ± 0.1 | +0.0 ± 0.1 | |
+15 | +0.0 ± 0.1 | −0.0 ± 0.1 | |
+30 | +0.2 ± 0.1 | +0.2 ± 0.1 | |
+45 | +0.3 ± 0.2 | +0.2 ± 0.1 | |
+60 | +0.4 ± 0.1* | +0.4 ± 0.1* |
The data are presented as mean ± SEM. There were 5 rats in each group.
P < 0.05, significant change from pre-value (Pre). There were no between group differences at any time point (P > 0.05, for all comparisons).