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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Biomed Pharmacother. 2021 Dec 22;146:112571. doi: 10.1016/j.biopha.2021.112571

Table 5.

Changes in body temperatures during various time points of the experimental protocol

Stage Time (min) Vehicle L-NAME

Pre −15 37.5 ± 0.1 37.4 ± 0.1
0 37.4 ± 0.1 37.4 ± 0.1
Average 37.5 ± 0.1 37.4 ± 0.1
Post-vehicle or L-NAME +5 37.6 ± 0.1 37.5 ± 0.1
+10 37.5 ± 0.1 37.5 ± 0.1
+15 37.4 ± 0.1 37.3 ± 0.1
Post-fentanyl +5 37.5 ± 0.1 37.4 ± 0.1
+10 37.6 ± 0.1 37.4 ± 0.1
+15 37.5 ± 0.1 37.3 ± 0.1
+30 37.7 ± 0.1 37.6 ± 0.2
+45 37.7 ± 0.2 37.6 ± 0.2
+60 37.9 ± 0.2 37.8 ± 0.1

Arithmetic changes from the average pre value

Post-vehicle or L-NAME +5 +0.1 ± 0.1 +0.0 ± 0.1
+10 0.0 ± 0.1 +0.0 ± 0.1
+15 0.0 ± 0.1 −0.0 ± 0.1
Post-fentanyl +5 0.0 ± 0.1 +0.0 ± 0.1
+10 +0.1 ± 0.1 +0.0 ± 0.1
+15 +0.0 ± 0.1 −0.0 ± 0.1
+30 +0.2 ± 0.1 +0.2 ± 0.1
+45 +0.3 ± 0.2 +0.2 ± 0.1
+60 +0.4 ± 0.1* +0.4 ± 0.1*

The data are presented as mean ± SEM. There were 5 rats in each group.

*

P < 0.05, significant change from pre-value (Pre). There were no between group differences at any time point (P > 0.05, for all comparisons).