Fig. 2.

Biome mapping to whole Ni-CODH phylogeny. A A phylogenetic tree of Ni-CODH clusters as shown in Fig. 1A mapped with three major biomes. The innermost ring represents clades of Ni-CODH clusters by colors as shown in Fig. 1A. The second inner ring indicates relative abundance of MGnify Ni-CODH sequences in each cluster by navy lines with color gradation. The outer three rings represent the presence of MGnify Ni-CODH sequences from three major biomes in the following order from inner to outer: green lines, "engineered"; blue lines, "environmental (aquatic)"; and magenta lines, "host-associated". B, C Clade compositions of Ni-CODH clusters (B) and principal component analysis (C) in the three major biome categories. D Principal component analysis of clade compositions of Ni-CODH clusters in the fourteen biome subcategories related to Fig. S4