Table 2.

Drift-diffusion model parameters in different brain disorders.

Disorder	Observed findings‡
PD	↓ bias changes, ↓ drift rate, ↑decision threshold, ↓ non-decision time
PD on medication	↑ decision thresholdand ↓ drift rates, Early termination of decisions (impulsivity), ↔ RT, ↓ premotor + motor timings
PD off medication	↓ RT
PD on STN-DBS	↓ premotor + motor timings, Early termination of evidence during STN-DBS
PD on GPi-DBS	↑RT, ↓ drift rate, ↑threshold, ↔ in conflict resolution
Schizophrenia	↓RT, ↓drift rate during punishment trials, ↔ bias, ↔ decision threshold, ↓ stimulus history utilization, ↑non-decision time, ↑ Working memory use
ASD	↔ RT, ↔ drift rate, ↔ accuracy, ↑ decision threshold, ↓ post-error RT
OCD	↑ decision threshold, ↑ drift rate with signal strength, ↓ drift rate in high signal-to-noise coherence, and ↓ threshold after a penalty compared to controls. ↓drift rate which ↑ with coherence. ↓drift rate in children. ↑ RT
ADHD	↓ drift rate which is ↔ after stimulant medication ↓ decision threshold in accuracy trials, ↑ decision threshold in speed trials. ↑ RT in accuracy trials, ↔ RT in speed trials.

^↑ increased;

^↓ decreased;

^↔no change.