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. 2022 Jan 20;12:1104. doi: 10.1038/s41598-021-04378-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Examples of raw single motor-evoked potentials (MEPs) from one HD participant (A) and one control participant (B) during rest, moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT). These MEPs were selected to illustrate the changes in cortico-motor excitability from baseline to post intermittent theta burst stimulation (iTBS) in the HIIT condition for control participants, but not HD participants.