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. 2022 Jan 20;12:1068. doi: 10.1038/s41598-022-05209-8

Table 2.

Type of adjuvant chemotherapy and treatment related adverse effects in women who received adjuvant trastuzumab.

Interventions/toxicity N = 39
Received chemotherapy
Docetaxel plus cyclophosphamide 30 (77)
Weekly paclitaxel × 12 4 (10)
5FU, epirubicin, and cyclophosphamide followed by docetaxel (FEC-DOC) 4 (10)
Doxorubicin plus cyclophosphamide followed by weekly paclitaxel × 12 1 (3)
Completed all planned cycles of chemotherapy 34a (87)
Febrile neutropenia 4 (10)
Completed one year of trastuzumab (17 or 18 treatments) 33 (85)
Asymptomatic drop in left ventricle ejection fraction 10 (26)
Symptomatic heart failure 0

a5 patients stopped chemotherapy early due to treatment related side-effects.