Table 4.
Cox Proportional univariate and multivariate analyses of factors associated with disease free survival in patients with T1a/bN0 HER2 + breast cancer.
| Variables | HR (95% CI) | HR (95% CI) |
|---|---|---|
| Univariate analysis | Multivariate analysis | |
| Age < 50 | 1.3 (0.30–5.9) | … |
| Comorbid illness | 1.0 (0.36–2.8) | … |
| ECOG performance status 1 | 1.02 (0.23–4.6) | … |
| Current smoking | 1.7 (0.37–7.8) | … |
| Hormone receptor positive | 1.9 (0.53–6.7) | … |
| Size | 1.02 (0.85–1.2) | … |
| T status | 1.4 (0.48–4.2) | … |
| Not received adjuvant trastuzumab | 2.0 (0.64–6.3), p = 0.23 | 3.0 (0.92–9.5) |
| Grade 3 | 4.9 (1.56–15.5), p = 0.007 | 5.5 (1.70–17.7) |
| Positive margin | 1.8 (0.39–7.9) | … |
| Not received Adjuvant endocrine therapy | 1.06 (0.37–3.0) | … |
| Not received adjuvant radiation | 1.5 (0.50–4.6) | … |
| Mastectomy | 2.4 (0.76–7.6), p = 0.13 | 1.9 (0.60–6.2) |
| HR using IPTW method | ||
| Not received adjuvant trastuzumab | 4 (1.05–15.5) | |
CI confidence interval, HR hazard ratio, IPTW inverse probability of treatment weighting.