Table 1.

Drug metadata.

Drug	Acronym	Drug Form	Purity	Concentration (μM)	Reference
Afatinib	AFA		98.8	0.05	27,28
Axitinib	AXI		98.0	0.20	29,30
Bosutinib	BOS		98.0	0.10	31
Cabozantinib	CAB		99.1	2.00	32
Dabrafenib	DAB		99.6	2.50	33,34
Dasatinib	DAS		98.4	0.10	35
Erlotinib	ERL		99.3	3.00	36,37
Gefitinib	GEF		99.3	1.00	38
Imatinib	IMA		99.5	5.00	39
Lapatinib	LAP		99.0	2.00	40
Nilotinib	NIL		99.8	3.00	41,42
Pazopanib	PAZ		96.1	10.0	43
Ponatinib	PON		97.3	0.10	44
Regorafenib	REG		99.6	1.00	45
Ruxolitinib	RUX		99.4	1.00	46,47
Sorafenib	SOR	Tosylate	99.7	0.50	46,47
Sunitinib	SUN	Malate	97.1	1.00	48,49
Trametinib	TRA		99.2	0.10	50
Tofacitinib	TOF	Citrate	99.9	1.00	50
Vandetanib	VAN		99.7	0.33	51
Vemurafenib	VEM		98.1	2.00	52

Purity was verified for each lot number. The concentration used for each drug is equivalent to the clinically-observed median peak plasma concentration as per the cited reference. Drugs are coded into different shades of a given color based on their primary target: purple (EGFR), orange (BCR-ABL), gray (VEGFR), red (JAK1/2), pink (MEK1/2), blue (multi-kinase).