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. 2022 Jan 20;12:1049. doi: 10.1038/s41598-022-05013-4

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© The Author(s) 2022, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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AURKA/B pathway genes associates with prognosis in WT p53 NSCLC patients. (A) Expression of the individual AURKA/B pathway genes that negatively correlates with RBL2 in NSCLC patients are tested for correlation with survival in all 994 NSCLC patients. High expression (≥ median) of each gene significantly associates with worse survival in WT p53 but not Mutant p53 patients (p values indicated). (B) High expression (≥ median) of E2F1 significantly associates with worse outcomes in WT p53 but not Mutant p53 patients (p values indicated).