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. 2021 Dec 13;12(1):195–202. doi: 10.1007/s13555-021-00643-4

Table 2.

Baseline disease characteristics of pooled dupilumab-treated “achiever” and “non-achiever” patients from SOLO 1 and 2

IGA 0/1 or EASI-75 at 16 weeks SOLO 1 and 2 dupilumab-treated patients
Non-achievers
(n = 391)
Achievers
(n = 529)
Duration of AD, years, mean ± SD 29.1 (15.0) 26.7 (15.4)
IGA score (range 0–4), mean ± SD 3.6 (0.5) 3.4 (0.5)
EASI total score (range 0–72), mean ± SD 35.7 (14.1) 29.9 (12.1)
Weekly peak pruritus NRS (range 1–10), mean ± SD 6.5 (1.8) 6.4 (2.0)
BSA affected (range 0–100), mean ± SD 58.9 (22.6) 50.0 (21.3)
POEM total score (range 0–28), means ± SD 21.4 (5.8) 19.8 (6.0)
Prior use of systemic immunosuppressants (including corticosteroids), n (%) 234 (59.8) 238 (45.0)

AD atopic dermatitis, BSA Body Surface Area Index, EASI Eczema Area and Severity Index, IGA Investigator’s Global Assessment, NRS numerical rating scale, POEM Patient-Oriented Eczema Measure, SD standard deviation