Table 2.
IGA 0/1 or EASI-75 at 16 weeks | SOLO 1 and 2 dupilumab-treated patients | |
---|---|---|
Non-achievers (n = 391) |
Achievers (n = 529) |
|
Duration of AD, years, mean ± SD | 29.1 (15.0) | 26.7 (15.4) |
IGA score (range 0–4), mean ± SD | 3.6 (0.5) | 3.4 (0.5) |
EASI total score (range 0–72), mean ± SD | 35.7 (14.1) | 29.9 (12.1) |
Weekly peak pruritus NRS (range 1–10), mean ± SD | 6.5 (1.8) | 6.4 (2.0) |
BSA affected (range 0–100), mean ± SD | 58.9 (22.6) | 50.0 (21.3) |
POEM total score (range 0–28), means ± SD | 21.4 (5.8) | 19.8 (6.0) |
Prior use of systemic immunosuppressants (including corticosteroids), n (%) | 234 (59.8) | 238 (45.0) |
AD atopic dermatitis, BSA Body Surface Area Index, EASI Eczema Area and Severity Index, IGA Investigator’s Global Assessment, NRS numerical rating scale, POEM Patient-Oriented Eczema Measure, SD standard deviation