Table 1.
Consecutive comparison of the Estimated Marginal Means (EMMs) of the linear mixed-effects models.
| Model | Tissue | Contrast | ΔEMM | SE | df | P-value |
|---|---|---|---|---|---|---|
| Volume (mm 3 ) | TIV | 5–3 | 152.77 | 4.11 | 197.95 | 0.0000 |
| 11–5 | 180.67 | 9.12 | 57.66 | 0.0000 | ||
| 17–11 | 91.99 | 9.42 | 68.16 | 0.0000 | ||
| Gray matter | 5–3 | 49.19 | 2.59 | 391.91 | 0.0000 | |
| 11–5 | 77.43 | 4.43 | 75.22 | 0.0000 | ||
| 17–11 | 24.52 | 4.82 | 103.13 | 0.0000 | ||
| White matter | 5–3 | 46.18 | 2.56 | 272.82 | 0.0000 | |
| 11–5 | 31.14 | 5.16 | 64.04 | 0.0000 | ||
| 17–11 | 33.14 | 5.42 | 79.88 | 0.0000 | ||
| CSF | 5–3 | 57.39 | 2.81 | 160.56 | 0.0000 | |
| 11–5 | 72.46 | 6.55 | 57.70 | 0.0000 | ||
| 17–11 | 34.78 | 6.72 | 65.24 | 0.0000 | ||
| Volume/TIV (%) | GM | 5–3 | −1.44 | 0.24 | 435.74 | 0.0000 |
| 11–5 | −0.51 | 0.26 | 446.47 | 0.1274 | ||
| 17–11 | −0.30 | 0.29 | 444.52 | 0.6175 | ||
| WM | 5–3 | 0.36 | 0.24 | 435.74 | 0.3253 | |
| 11–5 | −0.50 | 0.26 | 446.48 | 0.1377 | ||
| 17–11 | 0.40 | 0.29 | 444.52 | 0.3827 | ||
| CSF | 5–3 | 1.07 | 0.24 | 435.74 | 0.0000 | |
| 11–5 | 1.01 | 0.26 | 446.48 | 0.0003 | ||
| 17–11 | −0.10 | 0.29 | 444.52 | 0.9712 |
The difference in mm3 is reported for the volume models, while the percentage change relative to the total intracranial volume (TIV) is reported for the proportional model. ΔEMM denotes the difference in EMMs from the two sessions in the contrast column. SE, standard error. df, degrees of freedom.