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. 2022 Jan 7;12:758862. doi: 10.3389/fphys.2021.758862

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Copyright © 2022 Ko, Patnaik, Park, Kim, Baliarsingh, Jang, Lee, Han and Jo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tissue-specific induction patterns of Tenebrio NF-κB genes in TmIKKε dsRNA-treated T. molitor larvae against various pathogens. (A) Induction of TmRelish mRNA in the hemocytes, gut, and fat body of T. molitor larvae. (B) Induction of TmDorX1 mRNA in the hemocytes, gut, and fat body of TmIKKε-silenced T. molitor larvae. (C) Induction of TmDorX2 mRNA in the hemocytes, gut, and fat body of TmIKKε-silenced T. molitor larvae. Asterisks indicate significant differences between dsTmSpz5- and dsEGFP-treated groups when compared using Student’s t-test (p < 0.05).