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. 2022 Jan 7;12:797789. doi: 10.3389/fmicb.2021.797789

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Copyright © 2022 Gui and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Extrinsic apoptosis and necroptosis pathways during IAV infection. IAV infection can lead to upregulation of the death receptor ligands TNFα and FasL and the pattern recognition receptors TLR3/4 as well as downregulation of cFLIP.