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. 2022 Jan 20;136(2):167–180. doi: 10.1042/CS20210865

Figure 1. MCC950 increases renal injury in diabetic mice.

Figure 1

(A) Representative images of glomeruli sections stained with Periodic Acid–Schiff (scale bars indicating the length of 20 µm), (B) mesangial area per glomerulus and (C) GSI in the long-term study. Renal cortical gene expression of (D) P21 and (E) Pcna in the short-term study (10 weeks). C, control; D, diabetes; C+MCC950, MCC950-treated control and D+MCC950, MCC950-treated diabetic mice. Asterisks represents P-values for comparisons of the indicated groups: *<0.05 and ***<0.001. n=7–11/group.