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. 2022 Jan 7;12:795076. doi: 10.3389/fneur.2021.795076

Table 1.

Comparison between NCSE group and Non-NCSE group.

Variables All (n = 80) NCSE (n = 31) Non-NCSE (n = 49) P-value
Age, median (IQR) 78.5 (66.0,87.0) 83 (74.0,87.0) 76 (64.5–86.5) 0.148
Female, n (%) 44 (55.0%) 21 (67.7%) 23 (46.9%) 0.068
Hyper-early treatment, n (%) 51 (63.8%) 17 (54.8%) 34 (69.4%) 0.187
Low GCS score, n (%) 33 (41.3%) 18 (58.1%) 15 (30.6%) 0.015
State of consciousness 0.008
Lethargy, n (%) 32 (40.0%) 6 (19.4%) 26 (53.1%)
Stupor, n (%) 24 (30.0%) 11 (35.5%) 13 (26.5%)
Coma, n (%) 24 (30.0%) 14 (45.2%) 10 (20.4%)
Location of foci 0.724
Left, n (%) 22 (27.5%) 10 (32.3%) 12 (24.5%)
Right, n (%) 43 (53.8%) 16 (51.6%) 27 (55.1%)
Bilateral, n (%) 15 (18.8%) 5 (16.1%) 10 (20.4%)
Hemorrhagic transformation, n (%) 21 (26.3%) 11 (35.5%) 10 (20.4%) 0.135
Cortical injury, n (%) 49 (61.3%) 24 (77.4%) 25 (51.0%) 0.018
Atrial fibrillation, n (%) 43 (53.8%) 18 (58.1%) 25 (51.0%) 0.538
Diabetes, n (%) 25 (31.3%) 10 (32.3%) 15 (30.6%) 0.877
Hypertension, n (%) 61 (76.3%) 24 (77.4%) 37 (75.5%) 0.854
Smoking, n (%) 12 (15.0%) 2 (6.5%) 10 (20.4%) 0.167
BMI, mean ± SD 24.2 ± 4.0 23.6 ± 4.3 24.7 ± 3.8 0.204
hBA1C, median (IQR) 5.8 (5.4, 6.3) 5.7 (5.4,6.2) 5.8 (5.5,6.5) 0.181
Low-density lipoprotein, mean ± SD 2.8 ± 1.1 2.7 ± 0.9 2.8 ± 1.2 0.547
Homocysteine, median (IQR) 15.7 (11.8, 20.5) 17.1 (11.9,23.7) 14.9 (11.5,19.8) 0.432
Creatinine, median (IQR) 82.3 (61.2, 103.8) 83.0 (61.0,107.3) 80.6 (62.0,94.4) 0.671
Urea, median (IQR) 6.3 (4.7, 8.4) 7.1 (4.5,8.4) 6.1 (4.7,8.3) 0.898
Uric acid, mean ± SD 369.3 ± 130.6369 362.9 ± 134.8 373.3 ± 129.2 0.949
Neuron-specific enolase, median (IQR) 16.8 (14.0, 23.6) 17.8 (14.1,35.0) 16.4 (13.9,21.0) 0.189

NCSE, Non-convulsive status epilepticus; BMI, Body mass index; HbA1c, glycosylated hemoglobin.