Table 1.
Detailed characteristic of the studied cohorts.
| Characteristic | Train on 150 |
Validate on 87 |
||||
|---|---|---|---|---|---|---|
| Dead | Alive | p-value | Dead | Alive | p-value | |
| Age at RT in years [mean (Min-Max)] | 67 (24–92) | 68 (46–88) | 0.524 | 72 (50–88) | 67 (39–86) | 0.041 |
| Sex | ||||||
| Male | 39 (48.8 %) | 41 (51.2 %) | 0.844 | 31 (56.4 %) | 24 (43.6 %) | 0.392 |
| Female | 33 (47.1 %) | 37 (52.9 %) | 15 (46.9 %) | 17 (53.1 %) | ||
| WHO performance score | ||||||
| Restricted | 28 (40.0 %) | 42 (60.0 %) | 0.174 | 13 (46.4 %) | 15 (53.6 %) | 0.215 |
| Self-care | 29 (50.0 %) | 29 (50.0 %) | 17 (47.2 %) | 19 (52.8 %) | ||
| Limited Self-care | 14 (66.7 %) | 7 (33.3 %) | 16 (72.7 %) | 6 (27.3 %) | ||
| Missing | 1 (100 %) | 0(0.0 %) | 0 (0.0 %) | 1 (100 %) | ||
| Clinical profile | ||||||
| Favorable | 3 (8.8 %) | 31 (91.2 %) | <0.005 | 4 (28.6 %) | 10 (71.4 %) | 0.021 |
| Moderate | 15 (37.5 %) | 25 (62.5 %) | 11 (42.3 %) | 15 (57.7 %) | ||
| Unfavorable | 54 (71.1 %) | 22 (28.9 %) | 31 (66.0 %) | 16(34.0 %) | ||
| Location treated spinal metastases | ||||||
| Diffuse | 22 (66.7 %) | 11 (33.3 %) | 0.212 | 6 (46.2 %) | 7 (53.8 %) | 0.692 |
| Cervical | 4 (40.0 %) | 6 (60.0 %) | 2 (33.3 %) | 4 (66.7 %) | ||
| Lumbar | 23 (40.4 %) | 34 (59.6 %) | 15 (57.7 %) | 11 (42.3 %) | ||
| Thoracic | 23 (46.0 %) | 27 (54.0 %) | 23 (54.8 %) | 19 (45.2 %) | ||
| Number of spinal metastases | ||||||
| 1 | 15 (45.5 %) | 18 (54.5 %) | 0.486 | 10 (66.7 %) | 5 (33.3 %) | 0.308 |
| 2 | 17 (41.5 %) | 24 (58.5 %) | 07 (63.6 %) | 04 (36.4 %) | ||
| 3 or more | 40 (52.6 %) | 36 (47.4 %) | 29 (47.5 %) | 32 (52.5 %) | ||
| # of extra spinal bone metastases | ||||||
| None | 23 (46.9 %) | 26 (53.1 %) | 0.376 | 6 (60.0 %) | 4 (40.0 %) | 0.883 |
| 1 or 2 | 13 (61.9 %) | 8 (38.1 %) | 5 (50.0 %) | 5 (50.0 %) | ||
| 3 or more | 36 (45.0 %) | 44 (55.0 %) | 35 (52.2 %) | 32 (47.8 %) | ||
| Visceral metastases | ||||||
| Present | 32 (59.3 %) | 22 (40.7 %) | 0.038 | 26 (66.7 %) | 13 (33.3 %) | 0.020 |
| Not present | 40 (41.7 %) | 56 (58.3 %) | 20(41.7 %) | 28 (58.3 %) | ||
| Brain metastases | ||||||
| Present | 9 (100 %) | 0 (0.0 %) | 0.001 | 2 (100 %) | 0 (0.0 %) | 0.176 |
| Not present | 63 (44.7 %) | 78 (55.3 %) | 44 (51.8 %) | 41 (48.2 %) | ||
| Pain score | ||||||
| No pain | 1 (33.3 %) | 2 (66.7 %) | 0.251 | 1 (33.3 %) | 2 (66.7 %) | 0.784 |
| Mild | 2 (28.6 %) | 5 (71.4 %) | 2 (66.7 %) | 1 (33.3 %) | ||
| Moderate | 16 (64.0 %) | 9 (36.0 %) | 6 (60.0 %) | 4 (40.0 %) | ||
| Severe | 11 (45.8 %) | 13 (54.2 %) | 10(66.7 %) | 5 (33.3 %) | ||
| Very severe | 19 (48.7 %) | 20 (51.3 %) | 10 (43.5 %) | 13 (56.5 %) | ||
| Worst possible | 6 (75.0 %) | 2 (25.0 %) | 2 (40.0 %) | 3 (60.0 %) | ||
| Missing | 17 (38.6 %) | 27 (61.4 %) | 15 (53.6 %) | 13 (46.4 %) | ||
| Pathological fracture | ||||||
| Yes | 15 (50.0 %) | 15 (50.0 %) | 0.806 | 14 (53.8 %) | 12 (46.2 %) | 0.906 |
| No | 57 (47.5 %) | 63 (52.5 %) | 32(52.5 %) | 29 (47.5 %) | ||
| Spinal compression | ||||||
| Yes | 8 (28.6 %) | 20 (71.4 %) | 0.022 | 12 (54.5 %) | 10 (45.5 %) | 0.856 |
| No | 64 (52.5 %) | 58 (47.5 %) | 34 (52.3 %) | 31 (47.7 %) | ||
| lymphatic metastases | ||||||
| Present | 32 (53.3 %) | 28 (46.7 %) | 0.286 | 24 (53.3 %) | 21 (46.7 %) | 0.929 |
| Not present | 40 (44.4 %) | 50 (55.6 %) | 22 (52.4 %) | 20 (47.6 %) | ||
RT: Radiotherapy, #: Number.