Table 1.
The basic characteristics of the included studies
| Article, year | Number of researches centers | Total (n), UFH/Control |
Population | Age (Yr) | P value | |
|---|---|---|---|---|---|---|
| UFH | Control | |||||
| Deng et al, 2017 [22] | 1 |
118, 62/56 |
Sepsis and septic shock | 62.5 ± 13.9 | 61.5 ± 15.2 | P > 0.05 |
| Gu et al, 2014 [23] | 1 |
42, 21/21 |
Sever sepsis | 64.6 ± 12.7 | 69.7 ± 16.3 | P > 0.05 |
| Guo et al, 2019 [24] | 1 | 90,45/45 | Sepsis with pre-DIC | 64.75 ± 7.88 | 68.87 ± 6.16 | P > 0.05 |
| Hou et al, 2011 [25] | 1 |
40, 20/20 |
Sever sepsis | 58.6 ± 15.4 | 57.7 ± 12.6 | P > 0.05 |
| Jaimes et al, 2009 [26] | 1 |
319, 159/160 |
Sepsis | 57 (IQR: 39–70) | 55 (IQR: 40–72) | P > 0.05 |
| Levi et al, 2007 [27] | 224 |
1440, 485/955 |
Sever sepsis | 59.6 ± 16.1 | 58.4 ± 16.0 | P = 0.90 > 0.05 |
| Liu et al, 2014 [28] | 1 |
37, 22/15 |
Sepsis | 48.86 ± 14.3 | 47.47 ± 14.68 | P = 0.935 > 0.05 |
| Liu et al, 2009 [29] | 1 |
27, 12/15 |
Sepsis | 47.4 ± 16.8 | 48.3 ± 14.1 | P = 0.708 > 0.05 |
| Peng et al, 2013 [30] | 1 |
112, 56/56 |
Sepsis with pre-DIC | 63.5 ± 7.8 | 63.5 ± 7.8 | P > 0.05 |
| Wang et al, 2012 [31] | 1 |
48, 24/24 |
Sepsis | 52.7 ± 9.4 | 54.3 ± 8.6 | P > 0.05 |
| Wu et al, 2011 [32] | 1 |
85, 45/40 |
Sepsis | 68 ± 13 | 67 ± 14 | P = 0.684 > 0.05 |
| Zhang et al, 2006 [33] | 1 |
22, 11/11 |
Sever sepsis | 59.55 ± 6.15 | 59.36 ± 8.05 | P > 0.05 |
| Zhao et al, 2009 [34] | 1 |
79, 37/42 |
Sepsis | 61.5 ± 11.9 | 60.6 ± 15.9 | P > 0.05 |
| Zhao et al, 2007 [35] | 1 |
52, 27/25 |
Sever sepsis | NR | NR | P > 0.05 |
| Zhang et al, 2016 [36] | 1 |
106, 53/53 |
Sepsis | 43.5 ± 6.6 | 43.5 ± 6.6 | P > 0.05 |
NR not reported, UFH unfractionated heparin, IQR interquartile range