Table 1:
Composition of different cell types (exponential growth conditions)
| E. coli a | S. cerevisiae b | Mammalian Cell | |
|---|---|---|---|
| Water mass (% total mass) | 70 (70–74) | 68 (60–80) | 70 |
| Dry Mass (% total mass) | 30 (26–30) | 32 (20–40) | 30 |
| DNA (% dry mass) | 3 (1.6–3.4) | 0.3 (0.3–0.6) | 1 |
| RNA (% dry mass) | 21 (10–30) | 11 (6–12) | 4 |
| Protein (% dry mass) | 55 (42–76) | 51 (40–60) | 60 |
| Lipids (% dry mass) | 9 (9–10) | 7 (3–8) | 16 |
| Carbohydrates (% dry mass) | 8 (6.5–8) | 27 (17–50) | 7 |
| Inorganic Ions & Metabolites (% dry mass) | 4 | 4 (4–5) | 13 |
| References | [1,3,32,109,114–117] | [3,30,117–121] | [4,122] |
a
Values for E. coli grown at 37 °C in aerobic glucose containing minimal medium at a doubling time of 40 minutes [114]. Numbers in brackets indicate the range of reported values for various growth conditions.
b
Values for S. cerevisiae grown at 30 °C in aerobic 0.5% glucose containing minimal medium at a doubling time of 160 minutes [119]. Numbers in brackets indicate the range of reported values for various growth conditions.